Cell Disruption, also known as Cell Lysis, involves breaking the cell wall and/or membrane to release intracellular fluids containing desired molecules or particles, like proteins or viruses. The main objective is to efficiently break cells and recover the maximum viable yield of the target molecules/particles.
Mechanical methods for cell rupture involve tools like ball mills, blenders, and homogenizers. Ultrasonic disruption is effective but it is costly, also it is hard to make production level. PhD’s cell disruption technology offers precise control over forces like cavitation and shear, accommodating various sample sizes and cell types, ensuring reproducibility and scalability, with the PhD high pressure Homogenizer handling up to 40,000 PSI for extensive experimentation and potential production scale.