Nanotechnology has long been used in the pharmaceutical industry to improve bioavailability and ensure consistent dosing. Cannabinoids, as hydrophobic compounds, struggle with water solubility, causing instability and separation that lead to dosing and bioavailability challenges.

PhD high-pressure homogenizers equip formulators with the high-energy tools needed to create stable and bioavailable cannabinoid nanoparticles for both R&D and production. These formulations enhance stability, improve efficacy, and ensure consistent, reliable cannabinoid products for consumers and the industry alike.

Homogenizers Market to Reach USD 2.42 Billion by 2032 As Revealed In New Report.

The homogenizers market is a vital segment in the food and beverage, pharmaceutical, and cosmetic industries, driven by the need for consistent product quality and extended shelf life. Homogenizers are devices used to create a uniform mixture by breaking down particles in liquids, ensuring stability and uniformity in various products.

According to the SNS Insider report, The Homogenizers market Size is expected to witness a steady ascent, reaching an estimated USD 2.42 billion by 2032. That’s a significant jump from its 2024 valuation of USD 1.69 billion, fueled by a projected Compound Annual Growth Rate (CAGR) of 4.64% over the forecasted period (2024-2032)

Download Sample Copy of Report: www.snsinsider.com/sample-request/3421 

Top Key Players:

• Krones AG,
• Simes SA,
• GEA Group,
• Avestin Inc,
• Sonic Corporation,
• SPX Corporation,
• Microfluidics International Corporation,
• FPF Italia S.r.l,
• Ekato Holding GmBH,
• PHD Technology International LLC

PhD High-pressure homogenizers can generate the most consistent and stable cannabis emulsions, are suitable for both small-scale and production-scale applications.

There are currently four FDA-approved cannabinoid-related medicines, regulated to conform to GCP/GMP standards for consistent and reliable potencies and dosages. However, in basic research and the consumer market, consistency is often lacking. A recent test at the California Emerald Cup cannabis festival found only about 30 percent of CBD products contained the claimed percentage of CBD, and several tetrahydrocannabinol (THC) products had no active THC. These inconsistencies pose significant challenges, leading to severe reactions in users and difficulties in securing reliable suppliers for research labs.

Advanced homogenization techniques are crucial for consistency in cannabinoid products. Basic methods result in significant fluctuations in bioavailability and larger particle sizes, while high-pressure homogenization (HPH) and ultrasonic homogenization can achieve particle sizes under 100 nanometers, enhancing stability and bioavailability. PhD High Pressure Homogenizers by PhD Technology LLC are designed to meet compliance standards and improve product consistency. PhD High Pressure Homogenizers can reach up to 40000 psi. These technologies are essential for the cannabis industry’s growth, ensuring accurate potency measurements and reliable products for both research and consumers.

PhD High Pressure Homogenizer will attend Bio International 2024 with MN Deed Department.

The PhD high-pressure homogenizer, powered by 110V/220V/380V, 60/50 Hz, uses one or more pump plungers to create a reciprocating motion. Materials enter an adjustable pressure valve assembly, pass through a narrow gap, and are ejected at extremely high speeds (1000-1500 meters per second). This process involves cavitation, impact, and shear effects, resulting in uniform particle size reduction below 100nm and a cell disruption rate exceeding 97%.

High-pressure, high-speed solution hitting an impact ring experiences a sharp pressure drop, resulting in a significant pressure decrease. This leads to liquid vaporization, high-pressure bursting, and the consequent occurrence of the cavitation phenomena.

PhD high-pressure homogenizers have the following functionalities: temperature control, HMI system, quick cleaning feature, less waste of sample or products, CE or GMP requirement. High-pressure homogenizer technology has a great impact on Nano technology industries, which will bring the Nano technology to another level.

Pharmaceutical Formulation

In the pharmaceutical industry, preparations such as fat globules, microemulsion, liposomes, nano-suspension, nanoparticle, and microcapsules are produced.

Biological Application

Cell disruption and extraction of intracellular and extracellular substances in biotechnology products.

Daily Skincare

Homogeneous dispersion of the product can effectively enhance functionality, differentiate and increase added value, and ensure process stability, and more.

Fine Chemicals

Dispersion and separation of conductive slurries, resistive slurries, graphene, carbon nanotubes, nanometal oxides, and so on.

Nano Cannabinoid

The Nano Cannabinoid techniques have been shown to be effective in improving the delivery and the therapeutic effectiveness of drugs that are poorly soluble in water. Because the bioavailability of cannabinoids is low, the challenge is to explore different administration methods to improve their effectiveness. Because cannabinoids cross the blood-brain-barrier (BBB), they modify the negative effects of inflammatory processes on the BBB and may be a key factor in the improvement of BBB function.

Food Industry

Emerging food nanotechnology offers vast possibilities in packaging, and providing sensory information. Nano food packaging can extend shelf life, boost safety, detect contamination, repair tears, and release preservatives. Also nanofood, nanoparticles, nano-encapsulation will greatly offers the food industry a number of new approaches for improving the quality, shelf life, safety, and healthiness of foods. 

Cell Disruption, also known as Cell Lysis, involves breaking the cell wall and/or membrane to release intracellular fluids containing desired molecules or particles, like proteins or viruses. The main objective is to efficiently break cells and recover the maximum viable yield of the target molecules/particles.

Mechanical methods for cell rupture involve tools like ball mills, blenders, and homogenizers. Ultrasonic disruption is effective but it is costly, also it is hard to make production level. PhD’s cell disruption technology offers precise control over forces like cavitation and shear, accommodating various sample sizes and cell types, ensuring reproducibility and scalability, with the PhD high pressure Homogenizer handling up to 40,000 PSI for extensive experimentation and potential production scale.